ANTIHISTAMINES - A large group of medications that can block the effects of histamine on the cellular level. Widely used in the treatment of allergic disease. Some antihistamines are used to promote sleep. Examples of common generic and trade name antihistamines include diphenhydramine, carbinoxamine, pyrilamine, dimenhydrinate, triprolidine, azatadine, tripelennamine, dexchlorpheniramine, hydroxyzine, doxylamine, clemastine, chlorpheniramine, brompheniramine, Benadryl, Hismanal, Atarax, Actifed, and Seldane.